Cellulite affects approximately 85 percent of women and rarely men due to the hormone estrogent.Estrogen in the skin promotes fat storage and makes fat cells swell in size.Estrogen also breaks down the skin's collagen matrix. When fat cells sell up less blood flows into the area causing inflammation.Inflammation and break down of collagen makes the underlying skin structures weak permitting fat pockewts to protrude upward into the epidermis resulting in a dimpled appearance know as cellulite.